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A RNA nanotechnology platform for a simultaneous two-in-one siRNA delivery and its application in synergistic RNAi therapy

Incorporating multiple copies of two RNAi molecules into a single nanostructure in a precisely controlled manner can provide an efficient delivery tool to regulate multiple gene pathways in the relation of mutual dependence. Here, we show a RNA nanotechnology platform for a two-in-one RNAi delivery...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Jang, Mihue, Han, Hee Dong, Ahn, Hyung Jun
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999871/
https://ncbi.nlm.nih.gov/pubmed/27562435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32363
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