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Design of a platform technology for systemic delivery of siRNA to tumours using rolling circle transcription
For therapeutic applications of siRNA, there are technical challenges with respect to targeted and systemic delivery. We here report a new siRNA carrier, RNAtr NPs, in a way that multiple tandem copies of RNA hairpins as a result of rolling circle transcription (RCT) can be readily adapted in tumour...
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| Publicat a: | Nat Commun |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4918333/ https://ncbi.nlm.nih.gov/pubmed/26246279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8930 |
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