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Library siRNA-generating RNA nanosponges for gene silencing by complementary rolling circle transcription

Since the discovery of RNA interference (RNAi), small interfering RNA (siRNA) has been powerful tools for gene downregulation in biomedical applications. Despite the outstanding efficacy of siRNA, the development of a therapeutic delivery system remains a challenge owing to the instability of RNA. I...

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Vydáno v:Sci Rep
Hlavní autoři: Han, Sangwoo, Kim, Hyejin, Lee, Jong Bum
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577100/
https://ncbi.nlm.nih.gov/pubmed/28855687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10219-y
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