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LncSox4 promotes the self-renewal of liver tumour-initiating cells through Stat3-mediated Sox4 expression

Liver cancer has a tendency to develop asymptomatically in patients, so most patients are diagnosed at a later stage. Accumulating evidence implicates that liver tumour-initiating cells (TICs) as being responsible for liver cancer initiation and recurrence. However, the molecular mechanism of liver...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Chen, Zhen-zhen, Huang, Lan, Wu, Ya-hong, Zhai, Wen-jie, Zhu, Ping-ping, Gao, Yan-feng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999516/
https://ncbi.nlm.nih.gov/pubmed/27553854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12598
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