LncBRM initiates YAP1 signalling activation to drive self-renewal of liver cancer stem cells

Liver cancer stem cells (CSCs) may contribute to the high rate of recurrence and heterogeneity of hepatocellular carcinoma (HCC). However, the biology of hepatic CSCs remains largely undefined. Through analysis of transcriptome microarray data, we identify a long noncoding RNA (lncRNA) called lncBRM...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Zhu, Pingping, Wang, Yanying, Wu, Jiayi, Huang, Guanling, Liu, Benyu, Ye, Buqing, Du, Ying, Gao, Guangxia, Tian, Yong, He, Lei, Fan, Zusen
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5146280/
https://ncbi.nlm.nih.gov/pubmed/27905400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13608
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