LncBRM initiates YAP1 signalling activation to drive self-renewal of liver cancer stem cells

Liver cancer stem cells (CSCs) may contribute to the high rate of recurrence and heterogeneity of hepatocellular carcinoma (HCC). However, the biology of hepatic CSCs remains largely undefined. Through analysis of transcriptome microarray data, we identify a long noncoding RNA (lncRNA) called lncBRM...

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Vydáno v:Nat Commun
Hlavní autoři: Zhu, Pingping, Wang, Yanying, Wu, Jiayi, Huang, Guanling, Liu, Benyu, Ye, Buqing, Du, Ying, Gao, Guangxia, Tian, Yong, He, Lei, Fan, Zusen
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5146280/
https://ncbi.nlm.nih.gov/pubmed/27905400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13608
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