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Aurintricarboxylic acid structure modifications lead to reduction of inhibitory properties against virulence factor YopH and higher cytotoxicity

Yersinia sp. bacteria owe their viability and pathogenic virulence to the YopH factor, which is a highly active bacterial protein tyrosine phosphatase. Inhibition of YopH phosphatase results in the lack of Yersinia sp. pathogenicity. We have previously described that aurintricarboxylic acid inhibits...

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Bibliografski detalji
Izdano u:World J Microbiol Biotechnol
Glavni autori: Kuban-Jankowska, Alicja, Sahu, Kamlesh K., Gorska, Magdalena, Niedzialkowski, Pawel, Tuszynski, Jack A., Ossowski, Tadeusz, Wozniak, Michal
Format: Artigo
Jezik:Inglês
Izdano: Springer Netherlands 2016
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999467/
https://ncbi.nlm.nih.gov/pubmed/27562597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11274-016-2123-3
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