The Unusual Resistance of Avian Defensin AvBD7 to Proteolytic Enzymes Preserves Its Antibacterial Activity

Defensins are frontline peptides of mucosal immunity in the animal kingdom, including birds. Their resistance to proteolysis and their ensuing ability to maintain antimicrobial potential remains questionable and was therefore investigated. We have shown by bottom-up mass spectrometry analysis of pro...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Bailleul, Geoffrey, Kravtzoff, Amanda, Joulin-Giet, Alix, Lecaille, Fabien, Labas, Valérie, Meudal, Hervé, Loth, Karine, Teixeira-Gomes, Ana-Paula, Gilbert, Florence B., Coquet, Laurent, Jouenne, Thierry, Brömme, Dieter, Schouler, Catherine, Landon, Céline, Lalmanach, Gilles, Lalmanach, Anne-Christine
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999073/
https://ncbi.nlm.nih.gov/pubmed/27561012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161573
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