Regulation of TGF-β1-driven Differentiation of Human Lung Fibroblasts: EMERGING ROLES OF CATHEPSIN B AND CYSTATIN C

Lung matrix homeostasis partly depends on the fine regulation of proteolytic activities. We examined the expression of human cysteine cathepsins (Cats) and their relative contribution to TGF-β1-induced fibroblast differentiation into myofibroblasts. Assays were conducted using both primary fibroblas...

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Главные авторы: Kasabova, Mariana, Joulin-Giet, Alix, Lecaille, Fabien, Gilmore, Brendan F., Marchand-Adam, Sylvain, Saidi, Ahlame, Lalmanach, Gilles
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2014
Предметы:
Molecular Bases of Disease
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047393/
https://ncbi.nlm.nih.gov/pubmed/24790080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.542407
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