Glycolysis and the pentose phosphate pathway are differentially associated with the dichotomous regulation of glioblastoma cell migration versus proliferation

BACKGROUND: The dichotomy between glioblastoma cell migration and proliferation is regulated by various parameters including oxygen tension. In glioblastoma stem-like cells, hypoxia induces downregulation of pentose phosphate pathway (PPP) enzymes and a flux shift towards glycolysis. We investigated...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Kathagen-Buhmann, Annegret, Schulte, Alexander, Weller, Jonathan, Holz, Mareike, Herold-Mende, Christel, Glass, Rainer, Lamszus, Katrin
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
Basic and Translational Investigation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4998991/
https://ncbi.nlm.nih.gov/pubmed/26917237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now024
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki