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Glycolysis and the pentose phosphate pathway are differentially associated with the dichotomous regulation of glioblastoma cell migration versus proliferation

BACKGROUND: The dichotomy between glioblastoma cell migration and proliferation is regulated by various parameters including oxygen tension. In glioblastoma stem-like cells, hypoxia induces downregulation of pentose phosphate pathway (PPP) enzymes and a flux shift towards glycolysis. We investigated...

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Publicat a:Neuro Oncol
Autors principals: Kathagen-Buhmann, Annegret, Schulte, Alexander, Weller, Jonathan, Holz, Mareike, Herold-Mende, Christel, Glass, Rainer, Lamszus, Katrin
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4998991/
https://ncbi.nlm.nih.gov/pubmed/26917237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now024
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