Class I Histone Deacetylase Inhibition for the Treatment of Sustained Atrial Fibrillation

Current therapies are less effective for treating sustained/permanent versus paroxysmal atrial fibrillation (AF). We and others have previously shown that histone deacetylase (HDAC) inhibition reverses structural and electrical atrial remodeling in mice with inducible, paroxysmal-like AF. Here, we h...

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Bibliografiska uppgifter
I publikationen:J Pharmacol Exp Ther
Huvudupphovsmän: Seki, Mitsuru, LaCanna, Ryan, Powers, Jeffery C., Vrakas, Christine, Liu, Fang, Berretta, Remus, Chacko, Geena, Holten, John, Jadiya, Pooja, Wang, Tao, Arkles, Jeffery S., Copper, Joshua M., Houser, Steven R., Huang, Jianhe, Patel, Vickas V., Recchia, Fabio A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Pharmacology and Experimental Therapeutics 2016
Ämnen:
Cardiovascular
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4998670/
https://ncbi.nlm.nih.gov/pubmed/27353074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.116.234591
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