Class I Histone Deacetylase Inhibition for the Treatment of Sustained Atrial Fibrillation

Current therapies are less effective for treating sustained/permanent versus paroxysmal atrial fibrillation (AF). We and others have previously shown that histone deacetylase (HDAC) inhibition reverses structural and electrical atrial remodeling in mice with inducible, paroxysmal-like AF. Here, we h...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Seki, Mitsuru, LaCanna, Ryan, Powers, Jeffery C., Vrakas, Christine, Liu, Fang, Berretta, Remus, Chacko, Geena, Holten, John, Jadiya, Pooja, Wang, Tao, Arkles, Jeffery S., Copper, Joshua M., Houser, Steven R., Huang, Jianhe, Patel, Vickas V., Recchia, Fabio A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2016
Assuntos:
Cardiovascular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4998670/
https://ncbi.nlm.nih.gov/pubmed/27353074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.116.234591
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