Melatonin Treatment Improves Mesenchymal Stem Cells Therapy by Preserving Stemness during Long-term In Vitro Expansion

Mesenchymal stem cells (MSCs) are promising candidates for tissue regeneration and disease treatment. However, long-term in vitro passaging leads to stemness loss of MSCs, resulting in failure of MSCs therapy. Here, we report a melatonin-based strategy to improve cell therapy of in vitro cultured MS...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Shuai, Yi, Liao, Li, Su, Xiaoxia, Yu, Yang, Shao, Bingyi, Jing, Huan, Zhang, Xinjing, Deng, Zhihong, Jin, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4997245/
https://ncbi.nlm.nih.gov/pubmed/27570559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.15412
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