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Topology and structure of an engineered human cohesin complex bound to Pds5B

The cohesin subunits Smc1, Smc3 and Scc1 form large tripartite rings which mediate sister chromatid cohesion and chromatin structure. These are thought to entrap DNA with the help of the associated proteins SA1/2 and Pds5A/B. Structural information is available for parts of cohesin, but analyses of...

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Dettagli Bibliografici
Pubblicato in:Nat Commun
Autori principali: Hons, Michael T., Huis in ‘t Veld, Pim J., Kaesler, Jan, Rombaut, Pascaline, Schleiffer, Alexander, Herzog, Franz, Stark, Holger, Peters, Jan-Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4996973/
https://ncbi.nlm.nih.gov/pubmed/27549742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12523
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