Oxidative stress in the development, maintenance and resolution of paclitaxel-induced painful neuropathy

Paclitaxel is a first-line chemotherapeutic with the major dose-limiting side effect of painful neuropathy. Previous preclinical studies indicate mitochondrial dysfunction and oxidative stress are associated with this disorder; however no direct assessment of reactive oxygen species (ROS) levels and...

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Publicat a:Neuroscience
Autors principals: Duggett, Natalie A., Griffiths, Lisa A., McKenna, Olivia E., de Santis, Vittorio, Yongsanguanchai, Nutcha, Mokori, Esther B., Flatters, Sarah J.L.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Science 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4996646/
https://ncbi.nlm.nih.gov/pubmed/27393249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2016.06.050
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