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Pharmacological Modulation of the Mitochondrial Electron Transport Chain in Paclitaxel-Induced Painful Peripheral Neuropathy

Paclitaxel is an effective first-line chemotherapeutic with the major dose-limiting side effect of painful neuropathy. Mitochondrial dysfunction and oxidative stress have been implicated in paclitaxel-induced painful neuropathy. Here we show the effects of pharmacological modulation of mitochondrial...

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Detalhes bibliográficos
Publicado no:J Pain
Main Authors: Griffiths, Lisa A., Flatters, Sarah J.L.
Formato: Artigo
Idioma:Inglês
Publicado em: Churchill Livingstone 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596251/
https://ncbi.nlm.nih.gov/pubmed/26142652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2015.06.008
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