IL-31-Driven Skin Remodeling Involves Epidermal Cell Proliferation and Thickening That Lead to Impaired Skin-Barrier Function

Interleukin-31 (IL-31) is a type 2 helper T-cell-derived cytokine that has recently been shown to cause severe inflammation and tissue remodeling in multiple chronic diseases of the skin and lungs. IL-31 is upregulated in allergic and inflammatory diseases, including atopic dermatitis, asthma, cutan...

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Опубликовано в: :PLoS One
Главные авторы: Singh, Brijendra, Jegga, Anil G., Shanmukhappa, Kumar S., Edukulla, Ramakrishna, Khurana, Gurjit H., Medvedovic, Mario, Dillon, Stacey R., Madala, Satish K.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4996532/
https://ncbi.nlm.nih.gov/pubmed/27556734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161877
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