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Separation of retinoid-induced epidermal and dermal thickening from skin irritation

The ability of the synthetic retinoid MDI-301, in which the carboxylic acid of 9-cis-retinoic acid (9-cis-RA) is replaced with an ester linkage, to induce epidermal and dermal thickening and skin irritation (erythema and flaking) in hairless (rhino) mice following its topical application was investi...

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Autors principals: Varani, James, Fligiel, Helene, Zhang, Jian, Aslam, Muhammad Nadeem, Lu, Yi, Dehne, Lindsay A., Keller, Evan T.
Format: Artigo
Idioma:Inglês
Publicat: 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880508/
https://ncbi.nlm.nih.gov/pubmed/14564458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00403-003-0416-5
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