Declining Efficacy of Artemisinin Combination Therapy Against P. Falciparum Malaria on the Thai–Myanmar Border (2003–2013): The Role of Parasite Genetic Factors

Background. Deployment of mefloquine–artesunate (MAS3) on the Thailand–Myanmar border has led to a sustained reduction in falciparum malaria, although antimalarial efficacy has declined substantially in recent years. The role of Plasmodium falciparum K13 mutations (a marker of artemisinin resistance...

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Vydáno v:Clin Infect Dis
Hlavní autoři: Phyo, Aung Pyae, Ashley, Elizabeth A., Anderson, Tim J. C., Bozdech, Zbynek, Carrara, Verena I., Sriprawat, Kanlaya, Nair, Shalini, White, Marina McDew, Dziekan, Jerzy, Ling, Clare, Proux, Stephane, Konghahong, Kamonchanok, Jeeyapant, Atthanee, Woodrow, Charles J., Imwong, Mallika, McGready, Rose, Lwin, Khin Maung, Day, Nicholas P. J., White, Nicholas J., Nosten, Francois
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4996140/
https://ncbi.nlm.nih.gov/pubmed/27313266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciw388
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