Declining Efficacy of Artemisinin Combination Therapy Against P. Falciparum Malaria on the Thai–Myanmar Border (2003–2013): The Role of Parasite Genetic Factors

Background. Deployment of mefloquine–artesunate (MAS3) on the Thailand–Myanmar border has led to a sustained reduction in falciparum malaria, although antimalarial efficacy has declined substantially in recent years. The role of Plasmodium falciparum K13 mutations (a marker of artemisinin resistance...

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Detalhes bibliográficos
Publicado no:Clin Infect Dis
Main Authors: Phyo, Aung Pyae, Ashley, Elizabeth A., Anderson, Tim J. C., Bozdech, Zbynek, Carrara, Verena I., Sriprawat, Kanlaya, Nair, Shalini, White, Marina McDew, Dziekan, Jerzy, Ling, Clare, Proux, Stephane, Konghahong, Kamonchanok, Jeeyapant, Atthanee, Woodrow, Charles J., Imwong, Mallika, McGready, Rose, Lwin, Khin Maung, Day, Nicholas P. J., White, Nicholas J., Nosten, Francois
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Articles and Commentaries
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4996140/
https://ncbi.nlm.nih.gov/pubmed/27313266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciw388
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