Carbohydrate-binding domain of the POMGnT1 stem region modulates O-mannosylation sites of α-dystroglycan

The dystrophin glycoprotein complex, which connects the cell membrane to the basement membrane, is essential for a variety of biological events, including maintenance of muscle integrity. An O-mannose–type GalNAc-β1,3-GlcNAc-β1,4-(phosphate-6)-Man structure of α-dystroglycan (α-DG), a subunit of the...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Kuwabara, Naoyuki, Manya, Hiroshi, Yamada, Takeyuki, Tateno, Hiroaki, Kanagawa, Motoi, Kobayashi, Kazuhiro, Akasaka-Manya, Keiko, Hirose, Yuriko, Mizuno, Mamoru, Ikeguchi, Mitsunori, Toda, Tatsushi, Hirabayashi, Jun, Senda, Toshiya, Endo, Tamao, Kato, Ryuichi
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2016
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995984/
https://ncbi.nlm.nih.gov/pubmed/27493216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1525545113
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