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Long-Term Immunity to Trypanosoma cruzi in the Absence of Immunodominant trans-Sialidase-Specific CD8(+) T Cells

Trypanosoma cruzi infection drives the expansion of remarkably focused CD8(+) T cell responses targeting epitopes encoded by variant trans-sialidase (TS) genes. Infection of C57BL/6 mice with T. cruzi results in up to 40% of all CD8(+) T cells committed to recognition of the dominant TSKB20 and subd...

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Bibliografische gegevens
Gepubliceerd in:Infect Immun
Hoofdauteurs: Rosenberg, Charles S., Zhang, Weibo, Bustamante, Juan M., Tarleton, Rick L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995909/
https://ncbi.nlm.nih.gov/pubmed/27354447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00241-16
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