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CD8(+) T Cells Specific for Immunodominant Trans-sialidase Epitopes Contribute to Control of Trypanosoma cruzi Infection but are Not Required for Resistance
CD8(+) T cells are essential for controlling Trypanosoma cruzi infection. During Brazil strain infection, C57BL/6 mice expand parasite-specific CD8(+) T cells recognizing the dominant TSKB20 (ANYKFTLV) and sub-dominant TSKB74 (VNYDFTLV) trans-sialidase gene (TS)-encoded epitopes with up to 40% of al...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3784248/ https://ncbi.nlm.nih.gov/pubmed/20530265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000432 |
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