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CD8(+) T Cells Specific for Immunodominant Trans-sialidase Epitopes Contribute to Control of Trypanosoma cruzi Infection but are Not Required for Resistance

CD8(+) T cells are essential for controlling Trypanosoma cruzi infection. During Brazil strain infection, C57BL/6 mice expand parasite-specific CD8(+) T cells recognizing the dominant TSKB20 (ANYKFTLV) and sub-dominant TSKB74 (VNYDFTLV) trans-sialidase gene (TS)-encoded epitopes with up to 40% of al...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Rosenberg, Charles S., Martin, Diana L., Tarleton, Rick L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784248/
https://ncbi.nlm.nih.gov/pubmed/20530265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000432
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