CD8(+) T-Cell Responses to Trypanosoma cruzi Are Highly Focused on Strain-Variant trans-Sialidase Epitopes

CD8(+) T cells are crucial for control of a number of medically important protozoan parasites, including Trypanosoma cruzi, the agent of human Chagas disease. Yet, in contrast to the wealth of information from viral and bacterial infections, little is known about the antigen specificity or the gener...

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Autori principali: Martin, Diana L, Weatherly, D. Brent, Laucella, Susana A, Cabinian, Melissa A, Crim, Matthew T, Sullivan, Susan, Heiges, Mark, Craven, Sarah H, Rosenberg, Charles S, Collins, Matthew H, Sette, Alessandro, Postan, Miriam, Tarleton, Rick L
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2006
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1526708/
https://ncbi.nlm.nih.gov/pubmed/16879036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0020077
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