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A cell-based quantitative high-throughput image screening identified novel autophagy modulators

Macroautophagy is a major cellular degradation pathway for long-lived proteins and cellular organelles to maintain cellular homeostasis. Reduced autophagy has been implicated in neurodegenerative diseases, metabolic syndrome, and tumorigenesis. In contrast, increased autophagy has been shown to prot...

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Dades bibliogràfiques
Publicat a:Pharmacol Res
Autors principals: Li, Yuan, McGreal, Steven, Zhao, Jean, Huang, Ruili, Zhou, Yan, Zhong, Hua, Xia, Menghang, Ding, Wen-Xing
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995889/
https://ncbi.nlm.nih.gov/pubmed/27168224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2016.05.004
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