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Predictive Models for Cytochrome P450 Isozymes Based on Quantitative High Throughput Screening Data
The human cytochrome P450 (CYP450) isozymes are the most important enzymes in the body to metabolize many endogenous and exogenous substances including environmental toxins and therapeutic drugs. Any unnecessary interactions between a small molecule and CYP450 isozymes may raise a potential to disar...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3200453/ https://ncbi.nlm.nih.gov/pubmed/21905670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci200311w |
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