A carregar...
Use of human embryonic stem cells to model pediatric gliomas with H3.3K27M histone mutation
Over 70% of diffuse intrinsic pediatric gliomas, an aggressive brainstem tumor, harbor heterozygous mutations that create a K27M amino acid substitution (methionine replaces lysine 27) in the tail of histone H3.3. The role of the H3.3K27M mutation in tumorigenesis not fully understood. Here, we use...
Na minha lista:
| Publicado no: | Science |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4995593/ https://ncbi.nlm.nih.gov/pubmed/25525250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1253799 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|