Mitochondrial-targeted antioxidants protect against mechanical ventilation-induced diaphragm weakness

BACKGROUND: Mechanical ventilation (MV) is a life-saving intervention used to provide adequate pulmonary ventilation in patients suffering from respiratory failure. However, prolonged MV is associated with significant diaphragmatic weakness resulting from both myofiber atrophy and contractile dysfun...

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Vydáno v:Crit Care Med
Hlavní autoři: Powers, Scott K., Hudson, Matthew B., Nelson, W. Bradley, Talbert, Erin E., Min, Kisuk, Szeto, Hazel H., Kavazis, Andreas N., Smuder, Ashley J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995067/
https://ncbi.nlm.nih.gov/pubmed/21460706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0b013e3182190b62
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