Mitochondrial-targeted antioxidants protect against mechanical ventilation-induced diaphragm weakness

BACKGROUND: Mechanical ventilation (MV) is a life-saving intervention used to provide adequate pulmonary ventilation in patients suffering from respiratory failure. However, prolonged MV is associated with significant diaphragmatic weakness resulting from both myofiber atrophy and contractile dysfun...

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Bibliographic Details
Published in:Crit Care Med
Main Authors: Powers, Scott K., Hudson, Matthew B., Nelson, W. Bradley, Talbert, Erin E., Min, Kisuk, Szeto, Hazel H., Kavazis, Andreas N., Smuder, Ashley J.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995067/
https://ncbi.nlm.nih.gov/pubmed/21460706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0b013e3182190b62
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