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A novel in vitro platform for the study of SN38-induced mucosal damage and the development of Toll-like receptor 4-targeted therapeutic options

Tight junction and epithelial barrier disruption is a common trait of many gastrointestinal pathologies, including chemotherapy-induced gut toxicity. Currently, there are no validated in vitro models suitable for the study of chemotherapy-induced mucosal damage that allow paralleled functional and s...

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Detalhes bibliográficos
Publicado no:Exp Biol Med (Maywood)
Main Authors: Wardill, Hannah R, Gibson, Rachel J, Van Sebille, Ysabella ZA, Secombe, Kate R, Logan, Richard M, Bowen, Joanne M
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4994924/
https://ncbi.nlm.nih.gov/pubmed/27037276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370216640932
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