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WNK1 kinase balances T cell adhesion versus migration in vivo

Adhesion and migration of T cells are controlled by chemokines and by adhesion molecules, especially integrins, and play critical roles in the normal physiological function of T lymphocytes. Using an RNA interference screen we have identified the WNK1 kinase as a regulator of both integrin-mediated...

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Bibliografski detalji
Izdano u:Nat Immunol
Glavni autori: Köchl, Robert, Thelen, Flavian, Vanes, Lesley, Brazao, Tiago F., Fountain, Kathryn, Xie, Jian, Huang, Chou-Long, Lyck, Ruth, Stein, Jens V., Tybulewicz, Victor L. J.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4994873/
https://ncbi.nlm.nih.gov/pubmed/27400149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3495
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