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Critical roles for Rac GTPases in T-cell migration to and within lymph nodes

Naive T cells continuously recirculate between secondary lymphoid tissue via the blood and lymphatic systems, a process that maximizes the chances of an encounter between a T cell and its cognate antigen. This recirculation depends on signals from chemokine receptors, integrins, and the sphingosine-...

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Detalhes bibliográficos
Main Authors: Faroudi, Mustapha, Hons, Miroslav, Zachacz, Agnieszka, Dumont, Celine, Lyck, Ruth, Stein, Jens V., Tybulewicz, Victor L. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368586/
https://ncbi.nlm.nih.gov/pubmed/20870900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-08-299438
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