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Affinity for self antigen selects regulatory T cells with distinct functional properties
How regulatory T cells (T(reg) cell) control lymphocyte homeostasis is not fully understood. Here we identify two T(reg) cell populations with differing degrees of self-reactivity and distinct regulatory functions. Triple(hi) (GITR(hi)PD-1(hi)CD25(hi)) T(reg) cell are highly self-reactive and contro...
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| Publicado no: | Nat Immunol |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4994872/ https://ncbi.nlm.nih.gov/pubmed/27478940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3522 |
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