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Identification of an immediate Foxp3(−) precursor to Foxp3(+) regulatory T cells in peripheral lymphoid organs of nonmanipulated mice

CD4(+)CD25(+) regulatory T cells (T reg cells) expressing the transcription factor Foxp3 can be induced from peripheral T cell receptor (TCR) transgenic CD4(+)CD25(−)Foxp3(−) T cells stimulated with noninflammatory dendritic cells presenting low amounts of agonist cognate antigen. However, limited e...

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Detalhes bibliográficos
Main Authors: Schallenberg, Sonja, Tsai, Pei-Yun, Riewaldt, Julia, Kretschmer, Karsten
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901063/
https://ncbi.nlm.nih.gov/pubmed/20584884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100045
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