Listeria monocytogenes mutants defective in gallbladder replication represent safety-enhanced vaccine delivery platforms

The Gram positive intracellular pathogen Listeria monocytogenes represents a promising vaccine or therapeutic DNA delivery vector that has been successfully administered to humans in clinical trials. However in generating Listeria mutants with therapeutic potential it is important to balance safety...

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Dettagli Bibliografici
Pubblicato in:Hum Vaccin Immunother
Autori principali: Dowd, Georgina C., Bahey-el-din, Mohammed, Casey, Pat G., Joyce, Susan A., Hill, Colin, Gahan, Cormac G. M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2016
Soggetti:
Short Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4994736/
https://ncbi.nlm.nih.gov/pubmed/26905522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2016.1154248
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