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Listeria monocytogenes mutants defective in gallbladder replication represent safety-enhanced vaccine delivery platforms

The Gram positive intracellular pathogen Listeria monocytogenes represents a promising vaccine or therapeutic DNA delivery vector that has been successfully administered to humans in clinical trials. However in generating Listeria mutants with therapeutic potential it is important to balance safety...

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Bibliografiske detaljer
Udgivet i:Hum Vaccin Immunother
Main Authors: Dowd, Georgina C., Bahey-el-din, Mohammed, Casey, Pat G., Joyce, Susan A., Hill, Colin, Gahan, Cormac G. M.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4994736/
https://ncbi.nlm.nih.gov/pubmed/26905522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2016.1154248
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