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Listeria monocytogenes mutants defective in gallbladder replication represent safety-enhanced vaccine delivery platforms

The Gram positive intracellular pathogen Listeria monocytogenes represents a promising vaccine or therapeutic DNA delivery vector that has been successfully administered to humans in clinical trials. However in generating Listeria mutants with therapeutic potential it is important to balance safety...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Dowd, Georgina C., Bahey-el-din, Mohammed, Casey, Pat G., Joyce, Susan A., Hill, Colin, Gahan, Cormac G. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4994736/
https://ncbi.nlm.nih.gov/pubmed/26905522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2016.1154248
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