Variant rs10911021 that associates with coronary heart disease in type 2 diabetes, is associated with lower concentrations of circulating HDL cholesterol and large HDL particles but not with amino acids

AIMS: An intergenic locus on chromosome 1 (lead SNP rs10911021) was previously associated with coronary heart disease (CHD) in type 2 diabetes (T2D). Using data from the UCLEB consortium we investigated the relationship between rs10911021 and CHD in T2D, whether rs10911021 was associated with levels...

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Vydáno v:Cardiovasc Diabetol
Hlavní autoři: Beaney, Katherine E., Cooper, Jackie A., McLachlan, Stela, Wannamethee, S. Goya, Jefferis, Barbara J., Whincup, Peter, Ben-Shlomo, Yoav, Price, Jacqueline F., Kumari, Meena, Wong, Andrew, Ong, Ken, Hardy, Rebecca, Kuh, Diana, Kivimaki, Mika, Kangas, Antti J., Soininen, Pasi, Ala-Korpela, Mika, Drenos, Fotios, Humphries, Steve E.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Original Investigation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4994200/
https://ncbi.nlm.nih.gov/pubmed/27549350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-016-0435-0
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