Impaired HDL2-mediated cholesterol efflux is associated with metabolic syndrome in families with early onset coronary heart disease and low HDL-cholesterol level

OBJECTIVE: The potential of high-density lipoproteins (HDL) to facilitate cholesterol removal from arterial foam cells is a key function of HDL. We studied whether cholesterol efflux to serum and HDL subfractions is impaired in subjects with early coronary heart disease (CHD) or metabolic syndrome (...

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Udgivet i:PLoS One
Main Authors: Paavola, Timo, Kuusisto, Sanna, Jauhiainen, Matti, Kakko, Sakari, Kangas-Kontio, Tiia, Metso, Jari, Soininen, Pasi, Ala-Korpela, Mika, Bloigu, Risto, Hannuksela, Minna L., Savolainen, Markku J., Salonurmi, Tuire
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5313225/
https://ncbi.nlm.nih.gov/pubmed/28207870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171993
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