DNA Vaccines Encoding Antigen Targeted to MHC Class II Induce Influenza-Specific CD8(+) T Cell Responses, Enabling Faster Resolution of Influenza Disease

Current influenza vaccines are effective but imperfect, failing to cover against emerging strains of virus and requiring seasonal administration to protect against new strains. A key step to improving influenza vaccines is to improve our understanding of vaccine-induced protection. While it is clear...

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Опубликовано в: :Front Immunol
Главные авторы: Lambert, Laura, Kinnear, Ekaterina, McDonald, Jacqueline U., Grodeland, Gunnveig, Bogen, Bjarne, Stubsrud, Elisabeth, Lindeberg, Mona M., Fredriksen, Agnete Brunsvik, Tregoning, John S.
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2016
Предметы:
Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993793/
https://ncbi.nlm.nih.gov/pubmed/27602032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00321
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