DNA Vaccines Encoding Antigen Targeted to MHC Class II Induce Influenza-Specific CD8(+) T Cell Responses, Enabling Faster Resolution of Influenza Disease

Current influenza vaccines are effective but imperfect, failing to cover against emerging strains of virus and requiring seasonal administration to protect against new strains. A key step to improving influenza vaccines is to improve our understanding of vaccine-induced protection. While it is clear...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Lambert, Laura, Kinnear, Ekaterina, McDonald, Jacqueline U., Grodeland, Gunnveig, Bogen, Bjarne, Stubsrud, Elisabeth, Lindeberg, Mona M., Fredriksen, Agnete Brunsvik, Tregoning, John S.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993793/
https://ncbi.nlm.nih.gov/pubmed/27602032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00321
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