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Antigen Targeting to Human HLA Class II Molecules Increases Efficacy of DNA Vaccination
It has been difficult to translate promising results from DNA vaccination in mice to larger animals and humans. Previously, DNA vaccines encoding proteins that target Ag to MHC class II (MHC-II) molecules on APCs have been shown to induce rapid, enhanced, and long-lasting Ag-specific Ab titers in mi...
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Publicado no: | J Immunol |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
AAI
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5073356/ https://ncbi.nlm.nih.gov/pubmed/27671110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600893 |
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