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Controlling DNA-End Resection: An Emerging Task for Ubiquitin and SUMO
DNA double-strand breaks (DSBs) are one of the most detrimental lesions, as their incorrect or incomplete repair can lead to genomic instability, a hallmark of cancer. Cells have evolved two major competing DSB repair mechanisms: Homologous recombination (HR) and non-homologous end joining (NHEJ). H...
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| Udgivet i: | Front Genet |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4993767/ https://ncbi.nlm.nih.gov/pubmed/27602047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2016.00152 |
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