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How chimeric antigen receptor design affects adoptive T cell therapy
Chimeric antigen receptor (CAR) T cells have been developed to treat tumors and have shown great success against B cell malignancies. Exploiting modular designs and swappable domains, CARs can target an array of cell surface antigens and, upon receptor-ligand interactions, direct signaling cascades,...
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| Yayımlandı: | J Cell Physiol |
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| Asıl Yazarlar: | , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2016
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4993661/ https://ncbi.nlm.nih.gov/pubmed/27163336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.25419 |
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