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New structure-activity relationships of N-acetamide substituted pyrazolopyrimidines as pharmacological ligands of TSPO
Translocator protein (TSPO) represents an attractive target for molecular imaging and therapy due to its prevalence and critical roles played in oncology and other pathologies. Based upon our previously optimized pyrazolopyrimidine scaffold, we elucidated new structure activity relationships related...
Αποθηκεύτηκε σε:
Τόπος έκδοσης: | Bioorg Med Chem Lett |
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Κύριοι συγγραφείς: | , , , |
Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
2016
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4993599/ https://ncbi.nlm.nih.gov/pubmed/27353534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2016.06.041 |
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