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The New Dipeptide TSPO Ligands: Design, Synthesis and Structure–Anxiolytic Activity Relationship †
The translocator protein (TSPO, 18 kDa) plays an important role in the synthesis of neurosteroids by promoting the transport of cholesterol from the outer to the inner mitochondrial membrane, which is the rate-limiting step in neurosteroidogenesis. Stimulation of TSPO by appropriate ligands increase...
Guardat en:
| Publicat a: | Molecules |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7663781/ https://ncbi.nlm.nih.gov/pubmed/33158242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25215132 |
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