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BRCA2 mediates centrosome cohesion via an interaction with cytoplasmic dynein
BRCA2 is responsible for familial breast and ovarian cancer and has been linked to DNA repair and centrosome duplication. Here we analyzed the mechanism by which the centrosomal localization signal (CLS) of BRCA2 interacts with cytoplasmic dynein 1 to localize BRCA2 to the centrosome. In vitro pull-...
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| Publicado no: | Cell Cycle |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4993541/ https://ncbi.nlm.nih.gov/pubmed/27433848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1195531 |
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