BRCA2 mediates centrosome cohesion via an interaction with cytoplasmic dynein

BRCA2 is responsible for familial breast and ovarian cancer and has been linked to DNA repair and centrosome duplication. Here we analyzed the mechanism by which the centrosomal localization signal (CLS) of BRCA2 interacts with cytoplasmic dynein 1 to localize BRCA2 to the centrosome. In vitro pull-...

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Detaylı Bibliyografya
Yayımlandı:Cell Cycle
Asıl Yazarlar: Malik, Sadiya, Saito, Hiroko, Takaoka, Miho, Miki, Yoshio, Nakanishi, Akira
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2016
Konular:
Reports
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993541/
https://ncbi.nlm.nih.gov/pubmed/27433848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1195531
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