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Cytoplasmic Dynein-mediated Assembly of Pericentrin and γ Tubulin onto Centrosomes
Centrosome assembly is important for mitotic spindle formation and if defective may contribute to genomic instability in cancer. Here we show that in somatic cells centrosome assembly of two proteins involved in microtubule nucleation, pericentrin and γ tubulin, is inhibited in the absence of microt...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC14902/ https://ncbi.nlm.nih.gov/pubmed/10848628 |
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