Cytoplasmic Dynein-mediated Assembly of Pericentrin and γ Tubulin onto Centrosomes

Centrosome assembly is important for mitotic spindle formation and if defective may contribute to genomic instability in cancer. Here we show that in somatic cells centrosome assembly of two proteins involved in microtubule nucleation, pericentrin and γ tubulin, is inhibited in the absence of microt...

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Detalhes bibliográficos

Publicado no:	Mol Biol Cell
Principais autores:	Young, Aaron, Dictenberg, Jason B., Purohit, Aruna, Tuft, Richard, Doxsey, Stephen J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Cell Biology 2000
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14902/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10848628/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.11.6.2047
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