Clonal hematopoiesis as determined by the HUMARA assay is a marker for acquired mutations in epigenetic regulators in older women

Recent large cohort studies revealed that healthy older individuals harbor somatic mutations that increase their risk for hematologic malignancy and all-cause cardiovascular deaths. The majority of these mutations are in chromatin and epigenetic regulatory genes (CERGs). CERGs play a key role in reg...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Exp Hematol
Autori principali: Wiedmeier, J Erin, Kato, Catherine, Zhang, Zhenzhen, Lee, Hyunjung, Dunlap, Jennifer, Nutt, Eric, Rattray, Rogan, McKay, Sarah, Eide, Christopher, Press, Richard, Mori, Motomi, Druker, Brian, Dao, Kim-Hien
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993458/
https://ncbi.nlm.nih.gov/pubmed/27235757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2016.05.009
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi