Emergence of Clonal Hematopoiesis in the Majority of Patients with Acquired Aplastic Anemia

Acquired aplastic anemia (aAA) is a non-malignant disease caused by autoimmune destruction of early hematopoietic cells. Clonal hematopoiesis is a late complication, seen in 20–25% of older patients. We hypothesized that clonal hematopoiesis in aAA is a more general phenomenon, which can arise early...

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Detalhes bibliográficos
Publicado no:Cancer Genet
Main Authors: Babushok, Daria V., Perdigones, Nieves, Perin, Juan C., Olson, Timothy S., Ye, Wenda, Roth, Jacquelyn J., Lind, Curt, Cattier, Carine, Li, Yimei, Hartung, Helge, Paessler, Michele E., Frank, Dale M., Xie, Hongbo M., Cross, Shanna, Cockroft, Joshua D., Podsakoff, Gregory M., Monos, Dimitrios, Biegel, Jaclyn A., Mason, Philip J., Bessler, Monica
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433860/
https://ncbi.nlm.nih.gov/pubmed/25800665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cancergen.2015.01.007
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