Clonal hematopoiesis as determined by the HUMARA assay is a marker for acquired mutations in epigenetic regulators in older women

Recent large cohort studies revealed that healthy older individuals harbor somatic mutations that increase their risk for hematologic malignancy and all-cause cardiovascular deaths. The majority of these mutations are in chromatin and epigenetic regulatory genes (CERGs). CERGs play a key role in reg...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Exp Hematol
Main Authors: Wiedmeier, J Erin, Kato, Catherine, Zhang, Zhenzhen, Lee, Hyunjung, Dunlap, Jennifer, Nutt, Eric, Rattray, Rogan, McKay, Sarah, Eide, Christopher, Press, Richard, Mori, Motomi, Druker, Brian, Dao, Kim-Hien
Formato: Artigo
Idioma:Inglês
Publicado: 2016
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993458/
https://ncbi.nlm.nih.gov/pubmed/27235757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2016.05.009
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares